This on-demand course offers an in-depth analysis of three distinct medical cases encountered in the pro-football environment. Designed for medical professionals, the course delves into real-world scenarios involving exertional illness that deviate from typical presentations, emphasizing the critical decision-making processes under pressure. Participants will gain invaluable insights into recognizing nuanced signs of Exertional Heat Stroke (EHS), differentiating it from other conditions like sickling crises, and overcoming challenges related to diagnostic procedures and patient management. Through detailed case summaries, discussions of unique challenges, and key takeaways, the presentation aims to enhance preparedness, optimize patient care, and refine emergency action plans in high-stakes athletic settings.